A patient who has cerebral palsy is beginning to experience spasticity of the muscles in the upper arm. Which medications would the nurse question if prescribed for this patient?
1. Metaxalone (Skelaxin) dosed three times a day
2. Chlorzoxazone (Parafon Forte) dosed four times a day
3. Carisoprodol (Soma) dosed three times a day
4. Intrathecal baclofen (Lioresal)
5. Tizanidine (Zanaflex) dosed twice a day
Correct Answer: 1,2,5
Rationale 1: Metaxalone (Skelaxin) is ineffective in the treatment of spasticity-related neurologic disorders.
Rationale 2: Chlorzoxazone (Parafon Forte) is ineffective in the treatment of spasticity related to neurodegenerative disorders.
Rationale 3: Carisoprodol (Soma) is effective in relieving the pain, muscle spasms, and spasticity associated with cerebral palsy and is dosed three times a day.
Rationale 4: Baclofen (Lioresal) is effective in reducing muscle spasticity and can be delivered intrathecally.
Rationale 5: Tizanidine (Zanaflex) is used for muscle spasticity but has a short half-life and must be dosed every 6Â?8 hours.
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