Nitric oxide, a vasodilator produced by the vascular endothelium, is important in renal control by: Select all that apply
A) Preventing excessive vasoconstriction
B) Regulating renal blood flow
C) Inhibiting prostaglandin synthesis
D) Allowing normal excretion of sodium and water
Ans: A, D
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Nitric oxide, a vasodilator produced by the vascular endothelium, appears to be important in preventing excessive vasoconstriction of renal blood vessels and allowing normal excretion of sodium and water. Prostaglandins do not appear to play a major role in regulating renal blood flow. Some medications like aspirin and NSAIDs inhibit prostaglandin synthesis.
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