The rectal route is preferred over the oral route for certain emergency medications because:
A) rectal medications are altered significantly by first-pass metabolism.
B) bioavailability of rectal medications does not exceed 50 percent.
C) the vasculature of the rectal mucosa allows for slow drug absorption.
D) rectal medications are usually not subject to first-pass metabolism.
Answer: D) rectal medications are usually not subject to first-pass metabolism.
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The nurse is teaching a patient with a new prescription for alprazolam [Xanax]. Which statement is the most appropriate to include in the teaching plan?
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