Which of the following is(are) part of the fast-descending neuronal system for pain inhibition?
A. Rostral ventromedial medulla
B. Periaqueductal gray
C. Locus coeruleus
D. A, B, and C
E. None of the above
ANS: D
Rationale: The brainstem areas that provide intrinsic antinociception form a neuronal descending system, arising in the following: rostral ventromedial medulla, periaqueductal gray (PAG) in the midbrain, and locus coeruleus in the pons.
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