A nurse explains to a nursing student why opioid antidiarrheal medications are classified as drugs with little or no abuse potential. Which statement by the student indicates a need for further teaching?
a. "Formulations for the treatment of diarr-hea have very short half-lives."
b. "Opioid antidiarrheal drugs contain other drugs with unpleasant side effects at higher doses."
c. "Some opioid antidiarrheal drugs do not cross the blood-brain barrier."
d. "Some opioid antidiarrheal medications are not water soluble and cannot be given parenterally."
A
The half-life of the opioid antidiarrheal drugs is the same as that of the opioid analgesics. The formulations of opioid antidiarrheal medications that are classified with low abuse potential are often combined with atropine, which has unpleasant side effects at higher doses. Some opioid antidiarrheal drugs are formulated so that they do not cross the blood-brain barrier. Others are not water soluble and therefore cannot be dissolved and injected.
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