Drug half-life for an older child can be shortened because of increased metabolic rate. How does this affect the drug dose for older children versus that for adults?
a. It is increased because of drug metabolism.
b. It is decreased because of drug metabolism.
c. It is decreased because of an increased half-life.
d. It is the same as that for adults.
ANS: A
With a shorter half-life, more of the drug is eliminated quickly. This requires a higher dose of the medication.
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