The student nurse asks the instructor why a patient with a central nervous system infection is receiving antibiotics that will not cross the blood–brain barrier. What is the instructor's most correct response?
A) A severe infection alters the blood–brain barrier to allow the drug to cross.
B) A medication that is water soluble is more likely to cross the blood-brain barrier.
C) Antibiotics are the exception to the blood–brain barrier and cross easily.
D) An infection that spreads outside the central nervous system helps drugs cross the barrier.
A
Feedback:
Effective antibiotic treatment can occur only when the infection is severe enough to alter the blood–brain barrier and allow antibiotics to cross. Lipid-soluble, not water-soluble, medications cross the blood–brain barrier more easily and most antibiotics are lipid soluble, so they are not the exception. No matter where the infection originates, drugs must cross the blood–brain barrier to treat central nervous system infections.
You might also like to view...
A newborn assessment shows separated sagittal suture, oblique palpebral fissures, depressed nasal bridge, protruding tongue, and transverse palmar creases. These findings are most suggestive of
a. Microcephaly b. Down syndrome c. Cerebral palsy d. Fragile X syndrome
The nurse is teaching parents the signs of a hearing impairment in a child. What should the nurse include as signs? (Select all that apply.)
a. Outgoing behavior b. Yelling to express pleasure c. Asking to have statements repeated d. Foot stamping for vibratory sensation e. Failure to develop intelligible speech by age 24 months
Of the following, which is not an application of an EHR system?
A. capture of past social history B. capture of medication allergies C. capture of insurance policy number D. ability to send a prescription electronically
The two types of receptors that can be manipulated to reduce spasticity are the:
A. the histamine receptors and the cholinergic receptors. B. the alpha-2 adrenergic receptors and the GABA receptors. C. the serotonin receptors and the GABA receptors. D. alpha-1 adrenergic receptors and the GABA receptors.