Explain how ALL and Burkitt-type ALL are different morphologically
What will be an ideal response?
Answer:
ALL: Burkitt-type ALL
1. Small or large, homogeneous: Large/heterogeneous
2. Nuclear chromatin: fine or clumped: Nuclear chromatin: fine and homogeneous
to variable
3. Nuclear shape: occasional clefting: Nuclear shape: regular, oval to round
or indentation
4. Nucleoli: not visible to large and prominent: Nucleoli: prominent, one or more
5. Cytoplasm: scanty or abundant: Cytoplasm: moderately abundant
6. Basophilia: variable: Basophilia: very deep
7. Vacuolization: variable: Vacuolization: often prominent
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