Chaperones mediate nucleosome assembly. From the list below, what must happen first?

A. The CAF-1 chaperone binds an H3-H4 dimer and deposits it onto the DNA strand.
B. H3 and H4 form heterotetramers.
C. The NAP-1 chaperone assembles two H2A-H2B heterodimers with a H3-H4 tetramer.
D. The CAF-1 chaperone binds an H2A-H2B dimer and deposits it onto the DNA strand.


B

Biology & Microbiology

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