During DNA replication, DNA ligase is most active on the lagging strand. Why?
a. The lagging strands contain more short DNA segments than the leading strand, and these
short segments are joined together by DNA ligase.
b. The lagging strand is synthesized more slowly, and DNA ligase speeds up the DNA
polymerase.
c. The lagging strand synthesizes DNA in the 3' ? 5' direction.
d. The lagging strand requires DNA ligase to couple the RNA primer to the Okazaki
fragments.
e. The lagging strand has no RNA primase activity; it is replaced by DNA ligase.
A
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