A growth-hormone releasing hormone tumor in the brain could lead to stunted growth in children.
Answer the following statement true (T) or false (F)
False
Clarify Question
What is the key concept addressed by the question?
• This question is asking you to determine the impact of an increase in growth hormone releasing hormone.
What type of thinking is required?
• Apply level:
o You are being asked to take what you already know and use, or apply, it to a situation where there is an excess of the hormone that normally triggers the release of growth hormone and, therefore, growth.
Gather Content
What do you already know about the regulation of growth hormone? What other information is related to the question?
• To answer this question you need to recall that the secretion of hormones from the anterior pituitary gland is regulated by secretions from the hypothalamus. Further, you should note that the secretion of most anterior pituitary hormones is positively stimulated by the hypothalamus. This means that if the hypothalamus secretes a hormone the anterior pituitary gland will respond by secreting a specific hormone as well.
• Additionally, to answer this question you should recognize that if an anterior pituitary hormone is positively stimulated by a hypothalamic hormone then if more hypothalamic hormone is secreted more anterior pituitary hormone will be secreted.
• Finally, to answer this question you should recall that the role of growth hormone in children is to promote growth.
Choose Answer
Given what you now know, what information is most likely to produce the correct answer?
• At this point you should have everything you need to answer the question. The process of growth is regulated by growth hormone and growth hormone secretion is regulated by growth hormone releasing hormone from the hypothalamus. Therefore, if a tumor is producing an excess of growth hormone releasing hormone then there will be an excess of growth hormone and, subsequently, an increase in growth.
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?
• Apply level:
o Answering this question correctly depended on your ability to use the concept of positive stimulation of hormone release in a new situation. If you got an incorrect answer, did you remember that growth hormone is positively stimulated by growth hormone releasing hormone, or that an excess of growth hormone releasing hormone would result in excess growth hormone and, therefore, growth? Did you have trouble extending the concept of positive stimulation of hormone release to determine the correct answer?
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