The nurse has completed an admitting patient history and notes the patient's current medications to be simvastatin (Zocor) and warfarin (Coumadin). What is the result of the interaction of these drugs?
a. Abdominal distention
b. Increased INR
c. Low serum level of simvastatin
d. Hypertension
ANS: B
The combined therapy of simvastatin and warfarin may prolong the patient's INR. Additional nursing assessments would include monitoring for possible overcoagulation and bleeding. Abdominal distention and a low serum level of simvastatin do not occur with the combined therapy of simvastatin and warfarin. Increased blood pressure is not a complication of combining simvastatin and warfarin therapy.
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