The nurse is caring for a patient with moderate Alzheimer disease (AD). The health care provider has ordered memantine (Namenda) for the collaborative treatment of the patient's disease. What is the nurse's best understanding of this medication's action?

1. Protects cells against excess glutamate by partially blocking NMDA c-receptors.
2. Slows the degradation of acetylcholine, thereby increasing concentration of the neurotransmitters in the cerebral cortex.
3. Protects cells against excess NMDA by partially blocking glutamate c-receptors.
4. Slows the degradation of dopamine, thereby increasing concentration of the neurotransmitters in the cerebral cortex.


Answer: 1
Explanation: Memantine (Namenda) is a NMDA receptor antagonist. This medication may protect cells against excess glutamate by partially blocking NMDA c-receptors. Cholinesterase inhibitors (ChEIs) are also used in the treatment of AD. These medications slow the degradation of acetylcholine, thereby increasing concentration of the neurotransmitters in the cerebral cortex.

Nursing

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