In a lysosomal storage disease, newly synthesized lysosome hydrolases are secreted from the cells rather than being delivered to the lysosomes. What is one possible mechanism for this result?

A) The cis-Golgi network lacks a proton gradient.
B) The ER is unable to produce lysosomal vesicles.
C) Lysosomal enzymes are not phosphorylated in the rER.
D) Mannose is not phosphorylated in the cis-Golgi network.
E) All the hydrolase genes are mutated, resulting in synthesis by ribosomes free in the cytoplasm rather than on the endoplasmic reticulum membrane.


Answer: D

Biology & Microbiology

You might also like to view...

A gametophyte that develops from a ____ spore is bisexual, meaning that it can produce both sperm and eggs

a. homosporous b. polysporous c. heterosporous d. diplosporous e. bisporous

Biology & Microbiology

Which of the following is a hormone produced in the adrenal cortex that increases Na+ reabsorption in

the kidneys?

a. atrial natriuretic factor b. renin c. aldosterone d. antidiuretic hormone e. angiotensin

Biology & Microbiology

If an individual is heterozygous for a particular trait, the gametes that individual produces will contain 3/4 dominant and 1/4 recessive alleles.

Answer the following statement true (T) or false (F)

Biology & Microbiology

An example of a(n) drupe is an olive. Indicate whether the statement is true or false

Biology & Microbiology