Each of the following provides evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole except
A) Stabilization of microtubules with the drug paclitaxel stops chromosome movement to a pole.
B) Treatment that accelerates microtubule depolymerization causes chromosomes to move toward the poles more quickly.
C) Antibody inhibition of kinesin depolymerization of kinetochore microtubules interferes with chromosome movement to a pole.
D) Laser bleaching of labeled kinetochore microtubules indicates they shorten at the kinetochore as the chromosome moves toward a pole.
E) All of the above are evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole.
Answer: E
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