Which of these molecules could phosphorylate an unknown compound whose free energy of phosphate hydrolysis is -10.3kcal/mol?

Consider the following list of phosphorylated compounds with their free energies of phosphate hydrolysis:

Glucose-1-phosphate: -5.0 kcal/mol
PEP: -14.8 kcal/mole
ATP: -7.3 kcal/mol

A) Glucose-1-phosphate only
B) PEP only
C) ATP only
D) ATP and PEP
E) All three could phosphorylate the unknown compound.


Answer: B

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