The nurse is teaching a client about the role of calcium in hypertension, and explains that a high concentration of calcium in arterial smooth muscle cells leads to which clinical manifestation?

1. Elevated blood pressure
2. Hypercalcemia
3. Decreased blood pressure
4. Hypocalcemia


Correct Answer: 1
Rationale 1: Blood pressure is increased by the increase in contractility of vascular smooth muscle when intracellular calcium is increased.
Rationale 2: Hypercalcemia is not a consequence of intracellular calcium concentration, although a significant elevation in serum concentration of calcium can increase intracellular calcium.
Rationale 3: Calcium influx into vascular smooth muscle cells increases vasoconstriction and does not decrease blood pressure.
Rationale 4: Hypocalcemia is not a consequence of intracellular calcium concentration, although a significant decrease in serum concentration of calcium can decrease intracellular calcium.
Global Rationale: Blood pressure is increased by the increase in contractility of vascular smooth muscle when intracellular calcium is increased. Hypercalcemia is not a consequence of intracellular calcium concentration, although a significant elevation in serum concentration of calcium can increase intracellular calcium. Calcium influx into vascular smooth muscle cells increases vasoconstriction and does not decrease blood pressure.

Nursing

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