What is an indicator of how long a drug will produce its effect in the body?
1. Potency
2. Bioavailability
3. Half-life (t1/2)
4. Efficacy
3
Rationale 1: Potency refers to what dose of drug must be administered to achieve a certain level of response.
Rationale 2: Bioavailability is an index of what fraction of administered drug is absorbed and available to act in the body.
Rationale 3: Half-life(t1/2) is the time it takes the body to remove one-half of the drug from the circulation, and thus is a measure of how long the drug effect will last in the body.
Rationale 4: Efficacy refers to the magnitude of the response to a given dose of drug.
Global Rationale: Half-life (t1/2) is the time it takes the body to remove one-half of the drug from the circulation, and thus is a measure of how long the drug effect will last in the body. Potency refers to what dose of drug must be administered to achieve a certain level of response. Bioavailability is an index of what fraction of administered drug is absorbed and available to act in the body. Efficacy refers to the magnitude of the response to a given dose of drug.
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