You are interested in developing an inhibitor for the estrogen receptor. You have identified a molecule that is small and hydrophilic. In a test tube, this inhibitor binds tightly to the estrogen receptor and inhibits the interaction of the receptor with estrogen. Do you think that this molecule will be an effective inhibitor of the estrogen receptor in cells?
A. Yes, because it is small.
B. No, because it will need to bind to the DNA-binding domain to act as an inhibitor.
C. No, because it is hydrophilic.
D. Yes, because it can prevent estrogen binding.
Answer: C
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