A nurse is working as part of a team involved with the testing of a new psychiatric medication. The drug is currently being used in multiple clinical trials at various different sites. The nurse is engaged in which phase of testing?
A) Phase I
B) Phase II
C) Phase III
D) Phase IV
Ans: C
Phase III of new drug testing involves extensive clinical trials conducted at multiple sites throughout the country with large numbers of clients. This phase concludes with a new drug application being submitted to the U.S. Food and Drug Administration (FDA). Phase I testing defines the range of dosages tolerated in healthy individuals. Phase II testing studies the effects of the drug in a limited number of persons with the disorder, and defines a range of clinically effective dosages. Phase IV involves drug studies that continue after FDA approval to detect new or rare adverse reactions and potentially new indications.
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A patient who is lethargic and exhibits deep, rapid respirations has the following arterial blood gas (ABG) results: pH 7.32, PaO2 88 mm Hg, PaCO2 37 mm Hg, and HCO3 16 mEq/L. How should the nurse interpret these results?
a. Metabolic acidosis b. Metabolic alkalosis c. Respiratory acidosis d. Respiratory alkalosis
The nurse is planning a new parent education class for a group of adoptive parents. Which of the following is a priority topic for the class?
1. Chronic diseases in children 2. Congenital birth defects 3. Communicable childhood diseases 4. Accident prevention
A nurse researcher developed a nurse-driven intervention for patients with congestive heart failure and tested its effectiveness using an experimental design. This is an example of a:
A) Zelen intervention B) Attention-control intervention C) Patient-centered intervention D) Partially randomized patient preference intervention
A client recovering from anesthesia in the care unit has an artificial airway. The nurse knows the purpose of an artificial airway is to:
1. keep the mouth open. 2. keep the tongue from blocking the airway. 3. keep the client from vomiting. 4. allow the client to talk.