To be useful, a positive test should substantially:
1. Increase posttest probability.
2. Decrease posttest probability.
3. Increase pretest probability.
4. Increase pretest probability.
Increase posttest probability.
Rationale: To be useful, a positive test should substantially increase the posttest probability (likelihood that disease is present), and a negative test should lower the posttest probability. What is not always known is the pretest probability, which is the likelihood that disease is present in the client before testing.
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