Which statement by a patient indicates that the nurse's teaching about drug tolerance has been ineffective?
A) "If I stop the drug suddenly, withdrawal will occur."
B) "Drug tolerance means that I will need more drug to feel good."
C) "I take this drug because it makes me feel good."
D) "Drug tolerance develops after using the drug for the first time."
D) "Drug tolerance develops after using the drug for the first time."
Explanation: A) Symptoms of withdrawal, which vary among substances, are the defining characteristic of physical dependence on a substance.
B) Tolerance occurs as the body attempts to maintain homeostasis. After repeated use, the drug does not produce the same central nervous system effect as it did before, and thus more of the drug is needed to achieve the desired effect.
C) Increased levels of dopamine are associated with the feelings of well-being, exhilaration, and pleasure; consequently, the formation of positive memories and reinforcement for continued substance use occurs, leading to psychologic dependence. If the drug is unavailable, a state of uneasiness or dissatisfaction occurs, and the person may experience emotional or motivational withdrawal symptoms.
D) Tolerance occurs as the body attempts to maintain homeostasis. After repeated use, the drug does not produce the same central nervous system effect as it did before, and thus more of the drug is needed to achieve the desired effect.
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