Which of the following situations is most likely to result in an increased binding affinity of hemoglobin for oxygen?
A)
A client is in respiratory acidosis, with a low pH.
B)
Three of four binding sites on a client's hemoglobin molecule are occupied by oxygen.
C)
A client's body temperature is elevated as a result of an infectious process.
D)
An increase in 2,3-diphosphoglycerate enhances the loading of oxygen.
Ans:
B
Feedback:
As each binding site on a hemoglobin molecule is occupied, the affinity of the remaining sites for oxygen binding is increased. Increased affinity is associated with alkalosis, not acidosis, and fever causes reduced affinity. Exercise increases the unloading of oxygen, a situation characterized by low affinity.
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