Citrate synthase, the first enzyme in the citric acid cycle, is regulated by ATP concentrations. Why is early regulation
of ATP production the most beneficial method for the cell?
a. It is not possible to regulate the last enzyme in a pathway.
b. More ATP can be produced before the first enzyme is inactivated.
c. ATP production always needs to be maximized.
d. Citrate synthase controls the amount of pyruvate produced by glycolysis.
e. Regulating early steps conserves cellular fuels.
ANSWER: e
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