A self-limiting illness and the most common clinical syndrome associated with leptospirae that includes fever, headache, myalgia, and aseptic meningitis in the immune stage is called:
a. icteric leptospirosis.
b. anicteric leptospirosis.
c. Weil's disease.
d. syphilis.
B
Pathogenic leptospirae rapidly invade the bloodstream after entry and spread throughout all sites in the body such as the central nervous system and kidneys. Virulent strains show chemotaxis toward hemoglobin, as well as the ability to migrate through host tissues. Symptoms begin ab-ruptly 2 to 20 days after infection and include fever, headache, and myalgia. The most common clinical syndrome is anicteric leptospirosis, which is a self-limiting illness consisting of a septi-cemic stage, with high fever and severe headache that lasts 3 to 7 days, followed by the immune stage. Symptoms associated with the immune stage are varied, but, in general, they are more mild than the symptoms in the septicemic stage. The hallmark of the immune stage is aseptic meningitis.
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