Concerning abnormalities of chromosomes, nurses should be aware that:

1. they occur in approximately 10% of newborn infants.
2. abnormalities of number are the leading causes of pregnancy loss.
3. Down syndrome is a result of an abnormal chromosome structure.
4. unbalanced translocation results in a mild abnormality that the child will outgrow.


2
1. Incorrect. Chromosome abnormalities occur in less than 1 percent of newborn infants.
2. Correct. Aneuploidy is an abnormality of number that is also the leading genetic cause of mental retardation.
3. Incorrect. Down syndrome is the most common form of trisomal abnormality, an abnor-mality of chromosome number (47 chromosomes).
4. Incorrect. Unbalanced translocation is an abnormality of chromosome structure that often has serious clinical effects.

Nursing

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