Can you write an energy story for the overall process of glycolysis via the EMP pathway? For energy terms, just worry about describing things in terms of whether they are energy producing (exergonic) or energy consuming (endergonic). Make sure your story starts with glucose and ends with pyruvate.
What will be an ideal response?
In the EMP pathway, a glucose molecule undergoes a stepwise breakdown to two pyruvate molecules. The first part is an energy consuming (endergonic) process, where glucose is activated through two substrate phosphorylations by ATP, meaning that it uses up ATP initially. The direction of flow is determined by these key irreversible reactions that consume ATP. These steps drive the pathway by spending energy. Glucose is "activated" by phosphorylations that ultimately convert it into fructose-1,6 bisphosphate.
However, the breakdown of glucose to two molecules of pyruvate is ultimately an energy producing (exergonic) process, coupled to net production of two ATP and two NADH. Furthermore, in the cytoplasm, as intermediate products form they are quickly consumed by the next step, so the pathway flows in one direction.
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