A patient with an infection has not responded appreciably to antibiotic therapy, and the nurse suspects antibiotic resistance. What phenomenon is known to contribute to acquired antibiotic resistance?
A) Bacteria take on genetic material from healthy body cells, reducing antigen recognition.
B) Microorganisms remain in resting (G0) phase during antibiotic treatment.
C) Distribution of an antibiotic is insufficient to cause resolution of the infection.
D) The strongest microorganisms survive antibiotic treatment while the weakest are eradicated.
D
Feedback:
Selective pressure, or natural selection, refers to the survival of the fittest bacteria. When antibiotic therapy is initially begun, the weakest bacteria are killed first while the strongest bacteria, which are best able to withstand the effects of antibiotic therapy, remain. This contributes to antibiotic resistance. Resistance is not the result of an extended G0 phase, impaired distribution, or bacterial appropriation of human genetic material.
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