A patient with a severe systemic fungal infection will be treated with amphotericin B (Fungizone). What nursing interventions are required?

1. Administer the medication by IV push.
2. Give acetaminophen before giving the amphotericin B (Fungizone).
3. Review BUN level.
4. Give corticosteroids 1 hour after infusion is completed.
5. Monitor for gastrointestinal bleeding.


1,2,3
Rationale 1: This medication should be infused slowly to avoid cardiovascular collapse.
Rationale 2: Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction.
Rationale 3: The drug should be withheld if the BUN exceeds 40 g/dL.
Rationale 4: Corticosteroid administration should be part of pre-administration preparation.
Rationale 5: Gastrointestinal bleeding is not a concern.

Global Rationale: This medication should be infused slowly to avoid cardiovascular collapse. Giving acetaminophen prior to the infusion may decrease risk of hypersensitivity reaction. The drug should be withheld if the BUN exceeds 40 g/dL. Corticosteroid administration should be part of pre-administration preparation. Gastrointestinal bleeding is not a concern.

Nursing

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