An acquired hemorrhagic disorder that is characterized by excessive destruction of platelets is:
a. Aplastic anemia.
b. Thalassemia major.
c. Disseminated intravascular coagulation.
d. Idiopathic thrombocytopenic purpura.
ANS: D
Idiopathic thrombocytopenic purpura is an acquired hemorrhagic disorder characterized by an excessive destruction of platelets, discolorations caused by petechiae beneath the skin, and a normal bone marrow. Aplastic anemia refers to a bone marrow failure condition in which the formed elements of the blood are simultaneously depressed. Thalassemia major is a group of blood disorders characterized by deficiency in the production rate of specific hemoglobin globin chains. Disseminated intravascular coagulation is characterized by diffuse fibrin deposition in the microvasculature, consumption of coagulation factors, and endogenous generation of thrombin and plasma.
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