The nurse is caring for a patient prescribed aliskiren [Tekturna]. How does this medication lower blood pressure?
A. It blocks the conversion of angiotensin I to angiotensin II.
B. It prevents angiotensin II from binding to its receptors.
C. It inhibits the conversion of angiotensinogen into angiotensin I.
D. It selectively blocks aldosterone receptors in the kidneys.
Answer: C. It inhibits the conversion of angiotensinogen into angiotensin I.
Explanation: Aliskiren is the first direct renin inhibitor on the market. It binds with renin and thus inhibits the conversion of angiotensinogen to angiotensin I. The other items describe ACE inhibitors, ARBs, and selective aldosterone receptor blockers.
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