What is the primary mechanism for the anemia associated with kidney disease?
a. Hemolysis
b. Hemorrhage
c. Inadequate synthesis of erythropoietin
d. Inadequate synthesis of interleukins
ANS: C
Erythropoietin is the cytokine that has its primary effect on red cell production. It is synthesized in the kidney; thus when the kidney is diseased, erythropoietin synthesis is decreased. This decreases red cell production, leading to anemia.
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