A nurse is teaching a client about the relationship between calcium and PTH levels. Which best describes negative feedback in the homeostasis of the endocrine system?
1. As serum calcium levels decrease, PTH is decreased.
2. As serum calcium levels fall, PTH is released.
3. As serum calcium levels remain constant, PTH is decreased.
4. As serum calcium levels increase, PTH is increased.
2
Rationale 1:As serum calcium levels decrease, PTH is released, not decreased.
Rationale 2:This is the correct example of negative feedback.
Rationale 3:As serum calcium levels fall, PTH is released.
Rationale 4:As serum calcium levels fall, PTH is released.
Global Rationale: In the endocrine system, it is common for one hormone to control the secretion of another hormone. It is also common for the last hormone or action in the pathway to provide feedback. Most endocrine glands work by feedback inhibition in which the last hormone or action in the pathway prevents the production and release of the first hormone. As the serum calcium levels fall, PTH is released.
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