What body defense needs to be reduced in the patient following organ transplantation?
A) Major histocompatibility complex
B) Barrier defenses
C) Lymphoid tissues
D) Eosinophils
A
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The major histocompatability complex is the genetic identification code carried on chromosomes and produces several proteins called histocompatibility antigens located on the cell membrane that allow the body to recognize cells that are self-cells. Cells without these proteins, such as those in a transplanted organ, are identified as foreign and are targeted for destruction so this defense must be minimized to prevent damage to the transplanted organ. Barrier defenses prevent entry of pathogens into the body. Lymphoid tissue creates cellular components of the mononuclear phagocyte system, differentiates T cells, and regulates actions of the immune system. Eosinophils respond to allergic responses. Barrier defenses, lymphoid tissue, and eosinophils are not involved in the transplant rejection process.
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