What best describes the main determinant of the secondary structure of a protein?
A. The total number of polypeptide chains that combine to determine the overall size of the protein
B. The total number of amino acids that make up a polypeptide chain, and its overall resulting length
C. The sequence of the various amino acids that make up a polypeptide chain
D. Molecular interactions along a polypeptide chain that fold various regions into alpha helices or beta sheets
E. Molecular interactions between widely separated regions of a polypeptide, such as disulfide bonds, that stabilize the folded conformation
Answer: D
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