The nurse is caring for an older adult client with active tuberculosis (TB) who has a negative TB skin test. The nurse understands that this phenomenon is due to:
A) prior exposure to TB producing antibody immunity.
B) hyperactivity of the immune system occurring with active TB (anergy).
C) a diminished immune response due to changes in immunity occurring with age.
D) decreased immunity associated with treatment with immune-suppressive agents.
C) a diminished immune response due to changes in immunity occurring with age.
Explanation: A) The immune response is often diminished in older adults, owing to changes in the immune system that occur with age. This diminished responsiveness is called anergy, and it can result in a negative TB skin test, even when the client has active disease. It is not due to prior exposure to TB producing antibody immunity.
B) The immune response is often diminished in older adults, owing to changes in the immune system that occur with age. This diminished responsiveness is called anergy, and it can result in a negative TB skin test, even when the client has active disease. It is not due to hyperactivity of the immune system occurring with active TB, also called anergy.
C) The immune response is often diminished in older adults, owing to changes in the immune system that occur with age. This diminished responsiveness is called anergy, and it can result in a negative TB skin test, even when the client has active disease.
D) The immune response is often diminished in older adults, owing to changes in the immune system that occur with age. This diminished responsiveness is called anergy, and it can result in a negative TB skin test, even when the client has active disease. It is not due to decreased immunity associated with the treatment of active TB with immunosuppressants.
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