What is the action of zafirlukast (Accolate), a leukotriene receptor antagonist?
a. Dilates the alveolar sacs
b. Decreases leukotriene release
c. Inhibits histamine release
d. Increases viscosity of secretions
ANS: B
Leukotrienes are a class of anti-inflammatory agents that block leukotriene formation, and they are part of the inflammatory pathway that causes bronchoconstriction. Leukotrienes work to reduce bronchoconstriction, and they do not inhibit histamine release or affect viscosity of secretions.
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