A patient who is an opioid addict has undergone detoxification with buprenorphine (Subutex) and has been given a prescription for buprenorphine with naloxone (Suboxone). The patient asks the nurse why the drug was changed
Which response by the nurse is correct?
a. "Suboxone has a lower risk of abuse."
b. "Suboxone has a longer half-life."
c. "Subutex causes more respiratory depression."
d. "Subutex has more buprenorphine."
ANS: A
The combination of buprenorphine and naloxone (Suboxone) discourages intravenous abuse, because with IV use, the naloxone precipitates withdrawal; this effect does not occur with sublingual dosing (Subutex). Suboxone does not differ from Subutex in terms of drug half-life. Subutex does not cause more respiratory depression and does not contain more buprenorphine.
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