A couple wishes to know the chances of passing on an X-linked dominant heritable disorder to their four sons. The father's family has the disorder
The sons appear healthy, but the couple wants to be prepared for possible future events related to the disease. What information does the nurse give them?
A.
"All of them will be affected."
B.
"Half of them will be affected."
C.
"None of your sons will be affected."
D.
"One of the four will be affected."
ANS: C
An X-linked dominant inheritance disorder is the result of an alteration in a gene located on an X chromosome. None of this couple's sons can be affected because boys get a Y chromosome from the father, whereas all of a man's daughters will have it.
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