Which of the following clients should the nurse assess for a type III hypersensitivity immune responses resulting in injury to the vascular system? A client admitted with: Select all that apply
A) Extensive edema associated with acute glomerulonephritis
B) Newly diagnosed systemic lupus erythematosus (SLE)
C) Facial droop and impaired speech
D) Wheezing on inspiration
E) Liver failure exhibiting bleeding tendencies
Ans: A, B
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Type III responses create immune complexes that are deposited in the affected tissues, activating an inflammatory response. Autoantibodies are involved with type II responses; cytotoxic cells are involved with type II and type IV responses. Immunoglobulins are released in response to B-cell activation of plasma cells, which does not occur as part of type III reactions.
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