A couple who recently married and want to have children ask the nurse what the chances are that their children will inherit thalassemia from them, as they both are carriers. What information from the nurse is most accurate?
A.
All of your children will inherit it.
B.
Each child has a 25% chance of inheriting it.
C.
None of your children will inherit it.
D.
Only the boys will inherit it.
ANS: B
Thalassemia is an autosomal recessive disorder. Each of their children has a 25% chance of having only normal genes, a 25% chance of inheriting both defective genes from the parents and expressing the disease, and a 50% chance of being a carrier.
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