What initiates the sodium-potassium pump?
A. Two potassium ions are transported into the cell.
B. ATP binds to the protein which becomes phosphorylated (ADP is released).
C. Three sodium ions are translocated out of the cell.
D. Three sodium ions bind to the cytoplasmic side of the protein.
E. Phosphorylated pump has low affinity for sodium allowing sodium to leave and potassium to bind.
Answer: D
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