The DNA helicase animation shows the bacteriophage T7 helicase unwinding DNA. Which of the following are critical components of the helicase mechanism of action necessary to unwind DNA?
A. ATP binding and hydrolysis
B. binding of four helicase subunits to the double-stranded DNA
C. dissociation of the helicase subunits
D. conformational changes of subunits
E. oscillating loops pulling the single-stranded DNA through a central hole
Ans:
A. ATP binding and hydrolysis
D. conformational changes of subunits
E. oscillating loops pulling the single-stranded DNA through a central hole
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