A patient is admitted with a leg wound with a large amount of pus exudate. The nurse realizes the pus formation indicates
1. macrophages circulating in the blood.
2. neutrophils arrived at the wound as the first line of defense to remove foreign matter.
3. natural killer lymphocytes circulating through the lymph.
4. the complement system causing cellular destruction.
2
Rationale: Neutrophils are responsible for the formation of pus. As they die, the neutrophil degrading enzymes are released, causing breakdown and liquefaction of local cells as well as foreign substances. This forms pus, a thin liquid residue that is an important indicator of inflammation. Mobile macrophages circulate in the blood supply and migrate out of the vessels into the tissues when required through the process of chemotaxis. Natural killer lymphocytes protect the body from pathologic cells such as microbes and cancer cells through cytolytic activities and secretion of cytokines. The complement system is an immune mechanism that resembles the blood coagulation cascade by progressing through several sequential stages, each contributing to the immune response and resulting in cellular destruction or cytolysis. Neither macrophages, natural killer lymphocytes, nor the complement system create pus from an infected wound.
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