The nurse knows that client education on drug interactions with doxorubicin has been successful when the client states:
1. "I can take acetaminophen if I get a fever."
2. "I can take my Celebrex for my arthritis."
3. "I can take ibuprofen for my back pain."
4. "I can take an aspirin for a headache."
Correct Answer: 1
Rationale 1: Acetaminophen is appropriate to take, as it doesn't increase the risk of bleeding.
Rationale 2: Celebrex can cause bleeding when taken with doxorubicin due to its adverse effect of thrombocytopenia.
Rationale 3: Ibuprofen can cause bleeding when taken with doxorubicin due to its adverse effect of thrombocytopenia.
Rationale 4: Aspirin can cause bleeding when taken with doxorubicin due to its adverse effect of thrombocytopenia.
Global Rationale: Severe myelosuppression may occur with doxorubicin so medication that may increase bleeding (such as Celebrex, ibuprofen, and aspirin) should be avoided.
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