A nursing student is assigned to lead a class discussion on opioid antagonists. Which of the following would the student include as the mechanism by which opioid antagonists reverse the effects of opioid agonists? Select all that apply
A) Competitive inhibition of the opioid receptor
B) Direct binding to the opioid agonist
C) Displacement of the opioid agonist from the opioid receptor
D) Irreversible inhibition of the opioid receptor
E) Mutation of the opioid receptor
Ans: A, C
Feedback:
Opioid agonists reverse the opioid effects by competing for the opiate receptor site and displacing the opioid drug.
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