What problem exists when using the Harris-Benedict equation to calculate resting energy expenditure among patients with the same disease? I. This equation tends to overestimate resting energy expenditure (REE). II. The mean measured REE for mechanically ventilated patients can range from 70% to 140%. III. The equation was developed among healthy volunteers. IV. Multiple calculations must be

performed before a valid determination is made.

A. I, III only
B. II, IV only
C. I, II, III only
D. II, III, IV only


?ANS: B
A. Incorrect response: See explanation B.
B. Correct response: An inherent problem associated with using the Harris-Benedict equation for determining the resting energy expenditure (REE) is its tendency to underpredict the measured REE. Despite being developed using healthy volunteers, the Harris-Benedict equation remains useful. Patients receiving mechanical ventilation have been shown in one study to have a measured REE greater than 105% of predicted, ranging from 70% to 140% of predicted.
C. Incorrect response: See explanation B.
D. Incorrect response: See explanation B.

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