A nurse is assessing a graduate nurse's knowledge of antiepileptic medications and asks him, "How is ethosuximide (Zarontin) different from phenytoin (Dilantin) and carbamazepine (Tegretol)?"

Which response provided by the graduate nurse best demonstrates understanding of the differences between the medications?
a. Ethosuximide does not block sodium channels or enhance gamma-aminobutyric acid.
b. Ethosuximide efficacy is readily monitored by serum levels.
c. Ethosuximide has more significant adverse events and drug interactions.
d. Ethosuximide cannot be used in children.


ANS: A
Ethosuximide does not block sodium channels and does not enhance gamma-aminobutyric–mediated neuronal inhibition, as do phenytoin and carbamazepine.
All the drug levels should be monitored by serum levels.
The adverse events and drug interactions are not more significant with ethosuximide, and all share serious adverse side effects.
All of the medications may be used for children.

Nursing

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