The physician and advanced practice nurse are considering which antipsychotic medication to prescribe for a patient with schizophrenia who demonstrates auditory hallucinations, apathy, anhedonia, and poor social functioning
The patient is overweight and has hypertension. Bearing these facts in mind, the drug the nurse should advocate would be: a. clozapine (Clozaril).
b. haloperidol (Haldol).
c. olanzapine (Zyprexa).
d. aripiprazole (Abilify).
D
Aripiprazole is a new atypical antipsychotic effective against both positive and negative symptoms of schizophrenia. It causes little or no weight gain and no increase in glucose, high- or low-density lipoprotein cholesterol, or triglycerides, making it a reasonable choice for a patient with obesity or heart disease. Clozapine may produce agranulocytosis, making it a poor choice as a first-line agent. Haloperidol is unlikely to be effective against negative symptoms. Olanzapine fosters weight gain.
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