Identifying candidates for a disease gene by positional cloning depends on distinguishing DNA markers that are close to the disease gene from markers that are far away. When the disease gene is close to a marker, there will be

A) a high number of mutations in the intervening DNA.
B) a low rate of recombination between the disease gene and the marker.
C) many alleles at the marker locus.
D) a high chance of locus heterogeneity.


B) a low rate of recombination between the disease gene and the marker.

Biology & Microbiology

You might also like to view...

To discover the location of a genetic mutation that causes disease in humans, scientists use genetic mapping. Specifically, they look for genetic markers, or previously discovered ____ , that show ____ with the disease gene

Fill in the blank with the appropriate word.

Biology & Microbiology

Because glucose is a large molecule, it crosses the membrane through ____________________ diffusion. Fill in the blank(s) with the appropriate word(s)

Biology & Microbiology

Women who become pregnant are encouraged to take supplements of ________ because a deficiency in this nutrient can cause birth defects

A) vitamin K B) choline C) folic acid D) vitamin C E) biotin

Biology & Microbiology

A physician specializes in surgery involving the following group of organs: mouth, esophagus, stomach and intestines. Overall, this physician is specialized at which level of organization?

(a). cell (b). tissue (c). organ (d). organ system (e). organism

Biology & Microbiology